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Digital Slide Seminar 5: Day 2 (11.00 - 11.45)
Lupus nephritis - Prof Datuk Dr. Looi Lai Ming
32-year-old Chinese lady. Acute nephrotic syndrome (facial puffiness, generalized oedema) for 1 week. No stigmata of connective tissue disease. Denies drug ingestion. 24 hr urine protein 3.7 g. Acute urinary sediments. ?IgAN, ? Membranous, ? FSGS.
25-year-old Chinese lady. Mucocutaneous lesions, arthritis, low TWC, low platelets, ANF+, anti dsDNA+, Persistent proteinuria and haematuria. Alb 34, Cr 57, Hb 10.6. Lupus nephritis, Class?
21-year-old Chinese lady. ANA+, dsDNA+. Lupus nephritis?
17-year-old Chinese girl. Clinically SLE. ANA+. Hep B & C negative. Serum Alb 14.
29-year-old Malay lady. Diarrhoea, vomiting, epigastric pain for 2 weeks. Raised BP. Cr 1117, Hb 8.0. ANA+. UFEME: Protein 4+, RBC 5+,
37-year-old Chinese lady. ANA+, dsDNA 211u/mL. Proteinuria 0.5 g/24H. Initially no active urinary sediments but on follow up has 1 episode of hematuria. BP 148/78. Renal function normal. Cr 52. On prednisolone 40 mg daily, now tapering. ? LN Class i/II.