Digital Slide Seminar

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Henry D. Tazelaar, M.D.

Geraldine Colby Zeiler Professor of Cytopathology

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SYMP4C OD1: “Diffuse parenchymal lung disease case studies”

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Case 1:

• 34-year-old woman referred for the presence bilateral of pulmonary nodules

• ITP diagnosed at 8 yrs of age

• Splenectomy 1 yr PTA-reactive lymphoid hyperplasia and non-necrotizing granulomas

• Bronchoscopy x6!, all negative

• Fungal serology negative

• Case 1 - Digital Slide

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Case 2:

• 56-year-old woman with cough was found to have upper lobe pulmonary infiltrates

• Case 2 - Digital Slide

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Case 3:

• 35-year-old male smoker presented with upper lobe nodules on a screening radiograph. CT confirmed this and also identified some cystic changes

• Case 3 - Digital Slide

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Case 4:

• 61 yo M in previous good health with 6 mo of fatigue, progressive SOB, and lower extremety edema and pain

• Reported a 15 lb weight gain in 3 months

• Diminished breath sounds at bases

• Developed acute respiratory failure

• Lung biopsy

• Developed acute respiratory failure – intubation

• Exploratory right thoracotomy 

       - Right upper lobe biopsy

       - Pericardial window and biopsy

• Case 4 - Digital Slide

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